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Mechanistically, lactate activated the HIF-1/GPR81/mTOR/STAT3 signaling pathway in MDSCs, promoting their expansion and suppressive capacity (156)
10.1007/s11033-012-1783-9 132
Third, applying the method in the microplate reader is challenging due to the requirement for protein precipitation
A Therapeutic Use Exemption (TUE) will be necessary for any therapeutic use that exceeds these permitted limits
GSK-3beta manipulates ferroptosis sensitivity by dominating iron homeostasis
