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Its believed that this decline in production contributes to the onset of visible aging

PRP would require separate injections (and separate costs) at each site

Higher Bioavailability : The bioavailability of a drug refers to the proportion of the administered dose that reaches the systemic circulation and is available to exert its therapeutic effect

Greenway K (2014) Rituals in nursing: intramuscular injection

Neuroactive steroids are detectable in the brain after the removal of peripheral steroidogenic organs and their levels are affected by modifications in the levels of peripheral neuroactive steroids in a region-, time after gonadectomy- and sex-manner, suggesting a compensatory mechanism in the brain to counteract the effects of peripheral hormone loss (Caruso et al., 2010