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[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Patterson, S
This Cysteinyl-Glycine dipeptide can either be potentially transported via PEPT2 or cleave by dipeptidase releasing cysteine and glycine ( via ASCT family members but can also be oxidized and imported via xCT
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Meanwhile, research using human brain organoid models has demonstrated that ferroptosis inhibitors (Ferrostatin-1) can block A pathology, reduce lipid peroxidation and restore iron storage function in AD organoids (86)
PMID: 34609538
