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Chronic excess of cortisol in the brain may also lead to serotonin deficiency due to decreased availability of tryptophan, the substrate for serotonin production, and reduction of density and reactivity of serotonin receptors (252)

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Subcutaneous injections: Use small insulin-type needles Go into soft fatty tissue Allow slow, steady absorption Best Injection Sites Below are the most common and effective subcutaneous injection areas

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