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For example, the long-term supplementation of foods that are rich in omega-3 ( n-3 ) polyunsaturated fatty acids (PUFA) [285], vitamins such as vitamin A [286], B or folate [287], C, E [288], and D [289], carotenoids such as lutein and zeaxanthin [290,291], polyphenols [292], fiber [293], greater adherence to the Mediterranean diet, or a diet rich in vegetables and fruits (whole grains, nuts, tea, coffee, and legumes) or consumption of eggs, fish, seaweed, minerals such as copper, iron, magnesium, and calcium [294,295,296,297], delay the shortening of the TL in older adults through glycated hemoglobin (HbA1c) [284,288]

Its overactivity under oxidative stress exacerbates Ca 2+ overload, triggering mPTP opening, ATP depletion, and apoptosis [94,95,96]

Major advances in the management of relapsed/refractory multiple myeloma include BCMA-targeting treatments such as the CAR-T therapies ciltacabtagene autoleucel and idecabtagene vicleucel, and the bispecific antibodies teclistamab, elranatamab, and linvoseltamab

Myc, a common deregulated oncoprotein in cancer, is a challenging target due to its lack of enzymatic activity or structural features

These injections have been shown to boost energy, enhance mood, increase fat metabolism, improve sleep, strengthen and improve quality of hair and nails, as well as the skin
