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Screening and optimization of their modulators could lead to the development of medicine for modulating ferroptosis

Another possibility is that dietary restriction may indeed induce the expression of neuroprotective proteins in motor neurons, such as growth factors and stress proteins, but the pathogenic pathways involved in Cu/Zn SOD mutations are not affected by dietary restriction

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Therefore, current evidence does not indicate significant effects on bone metabolism, although most studies may not be long enough duration to determine increased risk of fractures or altered bone health

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