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The quantity of beta-amyloid plaques the brain continues to manufacture is reduced with aducanumab

Caspase and apoptosis pathways become activated through upregulation of CASP1, CASP3, CASP6, CASP7, CASP8, and CASP10 genes

R., Raj, S

The obese trial cohorts lost roughly 8% of body weight at 1 mg in Phase 2 and about 28% at 12 mg in the 80-week Phase 3 trial
