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If youre not currently exercising, Hyman recommends starting slow and building up to 30 minutes a day of vigorous aerobic exercise like walking, running, or others sports

For this reason, it is generally recommended that the therapeutic regimen be kept as simple as possible, since the risk of adverse effects is lower when one or two agents are given at higher doses as compared to a multiple-drug regimen using lower doses

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[30] Interestingly, and of particular importance for the potential of NSI-189 as a cognitive enhancer in healthy individuals, the drug was found to enhance long-term potentiation, a form of synaptic plasticity which underlies learning, in the hippocampus of wild-type (control) animals