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J.ZhangS.JohnsonC.KimberC.et al (2016)
Approximately 15% of Arg is metabolized in the liver and 60% in the gastrointestinal tract, and increased NO production through oral ingestion of Arg may be impaired [116]

New insights on the mechanisms of valproateinduced hyperammonemia: inhibition of hepatic Nacetylglutamate synthase activity by valproylCoA

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(PubMed) Nordstrom DC, Honkanen VE, Nasu Y, Antila E, Friman C, Konttinen YT
