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On the other hand, in spite of possible non-response, high-dose IVIG has the advantage in patients with high PRA on the waiting list of being less invasive given the unpredictable time to transplantation

Of note the prolonged treatment with BSO did not substantially affect the weight of treated mice, suggesting limited undesired effects associated with this regimen

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Nuclear-localized PKM2 has been shown to interact with G-quadraplex structures in pre-mRNAs which prevents the binding of repressive RNA binding proteins