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ROS can induce mitochondrial membrane permeabilization, leading to the release of cytochrome c, caspase activation, and, ultimately, programmed cell death 25
In most cells, the vast majority of ROS are generated in association with the mitochondrial electron transport system
In contrast, DFP possesses favorable lipid solubility and excellent BBB penetration, demonstrating more pronounced neuroprotective effects in AD animal models (Xi et al., 2022
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[24] Thanks Iodine tablets and other non-chlorine water treatments are not recommended, since they kill fewer microorganisms than chlorine
