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NRF-deficient dendritic cells have impaired GSH levels, reduced phagocytic activity, augmented expression of MHC class II, and enhanced co-stimulatory receptor expression of CD86 and CD80, thereby enhancing T cells stimulatory capacity [145]

[1] In practice, 1 mL (which provides the full 100 mg of B and B, etc.) is a common dose for general supplementation in deficient states, but clinicians may start with lower volumes for mild deficiencies or in smaller patients

Fgf22 protects hearing function from gentamycin ototoxicity by maintaining ribbon synapse number

J Neurosci 29:13274

[169] The review indicated that the severity of withdrawal symptoms is positively correlated with the age of the individual and the extent of their dependence