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No serious adverse effects were reported (death, hospitalization or emergency room visit)

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This variability in individual responses may stem from multiple factors, including genetics, metabolism, and physical constitution, highlighting the necessity for further in-depth research (159)

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C-peptide treatment from 5 to 8 months after DM onset showed an improvement in nerve conduction velocity (NCV) and axoglial dysjunction, normalization of paranodal demyelination, repair of axonal degeneration and a fourfold increase in nerve fiber regeneration [33]