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10.2217/pgs.13.142 58 DongL.WangW.LiA.KansalR.ChenY.ChenH.et al (2015)

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1 Introduction Globally, knee osteoarthritis (KOA) is one of the most commonly occurring disabling conditions, affecting over 364 million adults (Li et al., 2024), and it is widely recognized as the most prevalent and representative form of osteoarthritis (OA)

Although the use of targeted metabolite tracing, such as deuterium tracing of NADPH [7], is successful and remains the gold standard in the field, this approach requires mass-spectrometry, which may not be accessible to many laboratories

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Vance J.E