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Abbreviations (SNC-80): ((+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N-diethyl-benzamide) (CFA): complete Freund's adjuvant (DAMGO): [D-Ala(2), N-Me-Phe(4), Gly(5)-ol]-enkephalin (DORs): delta opioid receptors (DRG): dorsal root ganglion (ERK1/2): extracellular signalregulated kinases (GASP): G protein coupled receptor associated sorting protein (GIRK): G protein activated inward rectifier K+ (GPCRs): G protein-coupled receptors (LC): locus coeruleus (MORs): mu opioid receptors (AR-M1000390): N, NDiethyl- 4-(phenylpiperidin-4-ylidenemethyl) benzamide

Novel GLP-1-based Medications for Type 2 Diabetes and Obesity

doi: 10.1074/jbc.M202104200

Contact your healthcare provider if you notice any unusual reactions or side effects

Belosic Halle, K