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CT findings were classified as abnormal in the presence of a diffuse pattern of gray-white matter differentiation loss and sulcal effacement, corresponding to vascular territories in both anterior and posterior circulations, with involvement of the cerebral cortex and deep gray matter structures 14

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However, further research is needed to optimize treatment strategies, define optimal dosing regimens, and evaluate the long-term safety and neuroprotective efficacy associated with GlyT1 inhibition in cerebral ischemia

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