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The increased oxidative stress and impaired immune responses may be key for promoting cancer progression to advanced stages and may be induced by inflammatory mediators within the tumor (94)

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In addition, the decreased expression of antioxidant molecules in the hearts of non-obese diabetic mice was reported to act as an important factor that leads to the development of heart diseases ( Another interesting mechanism by which obesity affects the development of atherosclerosis through OS is Na/K-ATPase
