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Description
The high mortality rate of systemic aspergillosis (4090%) [83] is alarming

Ingredients like kojic dipalmitate and alpha arbutin commonly found in brightening soapshelp inhibit melanin production, the pigment responsible for dark spots

Treatments that claim to brighten focus either on slowing melanin production or speeding up the removal of pigmented cells

Examples include poly(N-isopropylacrylamide) (PNIPAM)-MSNs with thermo-responsive swelling for on-demand release of drugs and chitosan-MSNs with mucoadhesive character for oral delivery [73,74]

Swisher SG , Komaki R, Lynch PM, Ajani JA
