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That primaquine and other drugs can trigger acute haemolytic anaemia in subjects who have an inherited mutation of the glucose 6-phosphate dehydrogenase (G6PD) gene has been known for over half a century: however, these events still occur, because ...

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One of the most critical yet overlooked biochemical pathways is methylation, a process that affects detoxification, DNA repair, immune function, neurotransmitter balance, fertility and cardiovascular health. Central to the methylation process is the MTHFR (methylenetetrahydrofolate reductase) enzyme, which plays a []