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While methodological variability exists, the convergence of cellular, enzymatic, and histological endpoints strengthens the evidence supporting biologically meaningful redox modulation by GHK-Cu

In fact, geraniin, at a dose of 20 mg/kg injected intraperitoneally, was recently shown to ameliorate cisplatin-induced nephrotoxicity in mice by inhibiting OS and inflammatory response ( Geraniin has also been reported to exhibit neuroprotection in an in vitro study

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Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters