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Description
The synthesis process carefully manages the incorporation of alpha-aminoisobutyric acid (Aib) at the N-terminus and the D-amino acids (D-2-naphthylalanine and D-phenylalanine), which do not occur in natural proteins but are critical to the peptide's final properties
A structural insight
It also impairs parathyroid hormone release, leading to secondary hypocalcemia
WNT and beta-catenin signalling: diseases and therapies
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