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Assessment of heterogeneity among participants in the Parkinsons Progression Markers Initiative cohort using -synuclein seed amplification: a cross-sectional study

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Figure 3 2.3.1 AMPK and mTOR signaling pathways of autophagy regulation in SA-AKI As an initiator of autophagy, AMPK activates ULK1 by phosphorylating Ser 317 and Ser 777 of ULK1, thereby initiating the autophagy process and attenuating SA-AKI (77)