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According to a systematic review and meta-analysis of randomized controlled trials (RCTs), L-Carnitine supplementation significantly reduces body weight, Body Mass Index (BMI), and fat mass compared to control groups

2017 Feb;95(2):206-214

J Med Chem 65:59906000 Giuliani D, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Capolongo S, Sabba A, Galantucci M, Iannone A, Grieco P, Novellino E, Colombo G, Tomasi A, Catania A, Guarini S (2007) Selective Melanocortin Mc4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage

I dont know much about them, but you can also check out at home freezer fat removal systems that are available online

At least two biological replicates were done in each imaging experiment