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Yet despite their ubiquity, the basic biology underlying PAIS development, even for extensively studied PAIS such as myalgic encephalomyelitis/chronic fatigue syndrome, remains unclear 1,12

Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis

Acta 70 , 221230 (1963)

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The results revealed a significant increase in plasma PGA levels in TTR-V30M patients, whereas no significant elevation was observed in asymptomatic carriers or healthy controls
