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GTP turnover was then started by adding GTP (5 M) and GDP (10 M), and the amount of remaining GTP was assessed after 10 min incubation at 15 C using the GTPase-Glo assay (Promega)

MeasureUp has allowed us to give value to initiatives weve been doing for years, but couldnt properly evidence before. To illustrate this, Lucy shared a snippet of her Social Impact Report below to showcase the difference in social value measurement from 2023/24 to 2024/25 with MeasureUp now incorporated: Lucy explained the shift this created: Being able to put a figure on these activities transformed our bids

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Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion

Furthermore, mitochondrial dysfunction may contribute to the metabolic reprogramming of microglia through the activation of various signaling mechanisms