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[DOI] [PubMed] [Google Scholar] 5.Hasadsri L, Wang BH, Lee JV, Erdman JW, Llano DA, Barbey AK, et al

& Godbout, R

(145) reported that EDCs exert trans-generational effects on endocrine and metabolic function, as well as sperm epigenetic changes, including alterations in DNA methylation

This association remained strong even when comparing trends in peptide levels during the first year with changes in the fasting C-peptide/glucose ratio between the baseline 6 week and 24 month measurements (FDR=0.07)

Activation of ERK is dependent on the RAS/MAPK pathway, in which IIS results in phosphorylated IRS or SHC that recruit growth factor receptor-bound protein 2 (GRB-2)