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111,197,198 The mitochondrial apoptosis pathway is intricately linked to MOMP, which is predominantly regulated by BCL-2 family proteins, though it can also be triggered by the mPTP

As the GP activity was previously studied only in tissues such as rat liver and placenta without optimization of substrata conditions [7], the selection of blood as the target compartment to study the effect of systemic peroxide levels has the advantage of investigating the compartment subjected to all the comprehensive effects of peroxide systemic accumulation

2010;117:20672074.e6

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