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Therefore, in this review our aim is to bring all IGF-1 information regarding metabolism together with the objective of offering clear insight into the issuethis way clarifying how miss-regulation of the GH/IGF-1/insulin axis can lead to metabolic disorders such as MetS and diabetes

Metabolic reprogramming in gut microbiota exposed to polystyrene microplastics

Distinct from other forms of cell death, ferroptosis involves glutathione depletion, compromised glutathione peroxidase 4 (GPX4) activity, and unrestrained lipid peroxide accumulation, governed by intricate metabolic and signaling networks encompassing iron homeostasis, lipid metabolism, and pathways such as p53, MAPK, and Nrf2 (13, 14)