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Description
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FD patients as a group have comparable fasting plasma levels to those in health (95)
Sairanen J, Forsell T and Ruutu M: Long-term outcome of patients with interstitial cystitis treated with low dose cyclosporine a

However, the gastrointestinal side effects (vomiting, diarrhea) can cause dehydration that worsens kidney function

They arise not only in chronic users but also after a single dose, as cocaine has the capacity to lower seizure threshold, through a chronic low intensity stimulation of the limbic system (kindling) [83,89]