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Description
Long-term metformin treatment is associated with reduced serum B12 in a dose- and duration-dependent manner
Its role in preserving NAD+ and supporting mitochondrial health led to its use in advanced clinical longevity protocols as a tool to help protect NAD+
doi:10.1016/j.clnu.2020.11.035 9Andrs E, Affenberger S, Vinzio S, et al
IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms
Stress can negatively impact the absorption and utilization of vitamin B12, so finding healthy ways to manage stress is essential
