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Additionally, some bacterial metabolites can act as signaling molecules which induce the synthesis and release of neurotransmitters by enteroendocrine cells (Yano et al., 2015)

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As the airways progressively branch and narrow from the trachea to the alveoli, the aerodynamic size of inhaled aerosol particles is critical for their deposition site and extent in the lungs, primarily through mechanisms such as inertial impaction, gravitational sedimentation, and Brownian diffusion [23]