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Deborah Muoios lab at Duke University showed that loss of acylcarnitine processing in muscles leads to exercise intolerance, and work from our lab established that mice with a loss of CPT1 are intolerant to cold

CRITICAL STEP Step 45 provides the definitive measure of the concentration of functional IP 3 -binding sites (in mol ml 1 ), which is essential for FP analyses

Mice with hepcidin-resistant ferroportin accumulate iron in the retina

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They activate gene expression via intermediate signaling proteins such as Src, Ras, Rac/cdc42, and mixed lineage kinase protein families