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All samples from Ethiopia inherited the k1 ancestry, which was present at a minor proportion in some field Indian samples and a single Pakistan SDA500 colony sample (intermediate form)

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However, mitochondrial and metabolic dysfunction in CFS cannot be explained by the presence of circulating anti-mitochondrial autoantibodies (tested against the mitochondrial epitopes) (Nilsson et al

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In addition, high levels of VEGF and HIF-1 are linked with resistance to therapy and metastatic progression in clinical settings

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Nat Rev Immunol (2016) 16:55365.10.1038/nri.2016.70 6 BuckMDSowellRTKaechSMPearceEL

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