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The protein solution was buffer exchanged to Wash buffer 1 using HiPrep 26/10 Desalting column on an KTA Pure system (GE Healthcare) at room temperature

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In an earlier study, we treated juvenile rats with methylphenidate or amphetamine through the peripubertal period and discovered that the normal functional connections between the striatum, sensorimotor cortices and prefrontal cortex were reduced ( 9 -THC exposure and discontinuation on mice, awake or anesthetized, challenged with amphetamine

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Crucially, certain miRNAs exhibit aberrant expression patterns in the brain tissues and biofluids of PD patients or models, highlighting their potential as minimally invasive diagnostic or prognostic biomarkers

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