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Diabetic hyperglycemia further exacerbates this by suppressing astrocytic pentose phosphate pathway flux, which depletes nicotinamide adenine dinucleotide phosphate (NADPH) reserves [132, 133], a mechanism that mirrors defects in diabetic neuropathy where impaired redox defense amplifies oxidative injury

Subjects and methods Subjects This randomized, single-blinded, placebo-controlled clinical study was conducted in MetS patients at the First Affiliated Hospital of Sun Yat-Sen University in Guang Zhou, China and has been registered with the Chinese Clinical Trial Registry (No

Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2

It also feeds into the GABA shunt, an alternative metabolic pathway that produces Gamma-aminobutyric acid (GABA), the brain's primary inhibitory neurotransmitter