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It has been investigated for its effects on tendon-to-bone healing, gastrointestinal mucosal integrity, vascular development, and modulation of nitric oxide and growth-factor pathways in animal models
The increased vascular permeability can be detected by measuring the extravasation of Evans blue dye
Experimental studies examine receptor selectivity, downstream signalling pathways, and comparative responses relative to full-length erythropoietin
The effects were clearly dose-dependent, with higher doses producing better therapeutic outcomes
