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Description & Mechanism AOD9604 is a synthetic peptide derived from the C-terminal fragment (residues 176191) of human growth hormone (hGH), with sequence modifications introduced to enhance stability and research utility

In mice, a high-fat diet has also been shown to impair leptin signaling by attenuating STAT3 activation, thus contributing to leptin resistance [18].Leptin receptor activation engages intracellular proteins, such as protein tyrosine phosphatase1 B (PTP1B) and suppressor of cytokine signaling-3, that terminate receptor signaling