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For background on the broader angiotensin IV / AT4 system the work was built on, see Wright and Harding 1995 (PMID 7768321) and Wright et al
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Eur J Med Chem 98:203211
demonstrated weight loss (15.4%) after 20 weeks of cagrilintide therapy (4.5 mg/week) in combination with semaglutide (2.4 mg/week) [89]
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