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doi: 10.1016/j.freeradbiomed.2017.07.010 28 WeaverKSkoutaR

Calabrese V, Di Maio A, Marino G, Cardinale A, Natale G, De Rosa A, Campanelli F, Mancini M, Napolitano F, Avallone L et al (2020) Rapamycin, by Inhibiting mTORC1 Signaling, Prevents the Loss of Striatal Bidirectional Synaptic Plasticity in a Rat Model of L-DOPA-Induced Dyskinesia

Obviously this ignores all those who require life long treatment due to other causes of B12 deficiency (of which there are many), thereby potentially causing great harm to the vast majority of their B12 deficient patients

In contrast, a significant reduction in the granulomatous response was noted in M

In this context, understanding the molecular mechanisms underlying redox imbalance and its health implications is essential for the development of innovative therapeutic strategies