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A review of B vitamins and one-carbon metabolism highlights the importance of vitamin B12 and folate in the methylation cycle to generate methyl groups for use in DNA synthesis, amino acid homeostasis, antioxidant generation, and epigenetic regulation

After OGD treatment, the number of Ki-67-positive endothelial cells significantly decreased, while the intracellular expression levels of senescence markers P21, P53, and the DNA damage indicator -H2AX were markedly elevated (Figure 3B)

D., Smeal, S

[DOI] [PMC free article] [PubMed] [Google Scholar] 319.Brakedal, B

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