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Zinc has been implicated in the biological activity of enzymes, proteins, and signal transcription factors, as well as in the maintenance of various homeostatic mechanisms, acting as structural, regulatory, and catalytic cofactors for a variety of enzymes, such as DNA and RNA polymerases, histone deacetylases, and DNA ligases

The authors declare that the data supporting the findings of this study are available within the paper and its supplementary information files

Moreover, many natural Nrf2 activators can regulate lipid metabolism and oxidative stress of liver cells to alleviate fatty liver disease in mice

Pioneering studies indicate that targeting DNMTs could mitigate amyloid pathology (176)

PABA is an aromatic compound with a carboxylic and amino group attached to a benzene ring