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Data suggest that there is an increased incidence of congenital malformations associated with the use of valproate by women with seizure disorders during pregnancy when compared to the incidence in women with seizure disorders who do not use antiepileptic drugs during pregnancy, the incidence in women with seizure disorders who use other antiepileptic drugs, and the background incidence for the general population

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In the myocardium, fatty acid oxidation was inhibited, the glycolysis process was affected, the increase and circulation of TCA intermediates were in a poor status (the TCA metabolite ascending cycle is not smooth), and ATP production was decreased

The effects of l-Carnitine supplementation on inflammatory markers, clinical status, and 28 days mortality in critically ill patients: A double-blind, randomized, placebo-controlled trial