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They also act as antioxidants, promoting skin whitening, brightening
in this form it is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine (a reaction which also requires folate)
Cystinotic patients have been shown to excrete in their urine high levels of pyroglutamate, an intermediate metabolite of the adenosine triphosphate (ATP)dependent -glutamyl cycle, which is responsible for glutathione (GSH) synthesis
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