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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Valdivia A., Ly J., Gonzalez L., Hussain P., Saing T., Islamoglu H., Pearce D., Ochoa C., Venketaraman V

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These studies generally demonstrate favorable safety profiles, although their therapeutic efficacy is often limited by poor aqueous solubility, rapid metabolism, and low systemic bioavailability

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