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The global prevalence of diabetes has increased significantly, leading to various complications and a negative impact on quality of life
Further studies are required to understand the molecular targets involved in methotrexate- induced hepatotoxicity, as well as to translate into therapeutic approaches
Notably, islet incubation with FGF-21 was able to restore insulin secretion after in vitro Taz-KD
Data on dermal toxicity caused by copper compounds is scant
