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This has been called out as a contributing factor to patient anxiety

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Due to its high content of CRH neurons and elevated expression of CRH-, MR-, and GRs, the hippocampus is particularly sensitive to the action of stress hormones [134]

5.9 miR-17-5p Neuronal cell viability was altered and paraquat-induced neuronal apoptosis was reversed due to the release of exosomes by microglia

Chanda J, Mukherjee PK, Biswas R, Biswas S, Tiwari AK, Pargaonkar A (2019) UPLC-QTOF-MS analysis of a carbonic anhydrase-inhibiting extract and fractions of Luffa acutangula (L.) Roxb (ridge gourd)