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Furthermore, 10 mM keto--methylvaleric acid (KMV) was used as a control to demonstrate complete inhibition of the OGDHc in vitro

The colonic muscle is the most oxygenated region with 7%10% oxygen levels (Schwerdtfeger et al., 2019)

Funding This work was supported by the Zhejiang Medicine and Health Research Fund Project under Grant No

The transcription factor myc controls metabolic reprogramming upon T lymphocyte activation

24 Moreover, vitamin C can bear therapeutic potential for cancer treatment through the activation of tumour suppressor genes like p53 and p21 which are associated with cell cycle arrest and inhibition of cancer proliferation