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Regardless of the initial trigger, common causes of gut failure in critical illness include compromised GI blood supply, lymphatic dysfunction, epithelial damage, and alterations in the gut microbiota

Heres a breakdown of top contenders, how they work and some recent preclinical data to justify more investigation

Frank suggested oral tranexamic acid (yep, the same stuff in that serum, but in pill form)

Accordingly, administration of folic acid in combination with vitamins B 6 and B 12 improved endothelial dysfunction subsequent to hyperhomocysteinemia induced by methionine loading in healthy humans (Chao et al, 1999a)

With 110 cases, MIS is not super rare, at least among those kids who are sick enough to get to the hospital