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in a larger Ladakhi cohort, which revealed that seven EGLN1 polymorphisms (rs1538664, rs479200, rs2486729, rs2790879, rs480902, rs2486736 and rs973252) were strongly correlated with HAPE susceptibility

Thats why supplementation matters

No human trials on AOD-9604 for joint health have been published

Notes 12 , 446 (2019)

L-ascorbic acid requires a low pH (typically below 3.5) to remain stable, and that acidic environment can disrupt the copper complex in GHK-Cu, potentially degrading both ingredients
