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Inflammation is intensified by the release of pro-inflammatory cytokines that are secondary to barrier disruption, mechanical factors (scratching and friction), and the application of irritants or sensitizers in topical preparations or skin care products

Some of the most common thermo-responsive polymers used to prepare IN gel formulations include poloxamers (poloxamer 188 and poloxamer 407) and chitosan [26,27]

10.2174/1568026621666210113165007 Summary Keywords natural flavonoids, atopic dermatitis, botanical drugs, multi-target pharmacological actions, novel drug delivery systems Citation Li D, Han Y, Zhou J, Chen J, Tey HL and Tan TTY (2025) Flavonoids in atopic dermatitis: mechanisms, delivery innovations, and translational strategies
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aeruginosa biofilms were formed together with PMN cells in vitro, the PMN localized to the biofilm surface but had very little microbicidal activity (Rasamiravaka et al

Importantly, the observed inhibition of AMPK phosphorylation by EtOH in WT mice was absent from KO mice (Fig